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Terlipresresn acetate ya esophageal magazi

Kufotokozera kwaifupi:

Dzinalo: N-(N-(N-Glycyllcyl) Glycyl) -8-l-lysinevasopressin

Nambala ya Cas: 1463-12-5

Mawonekedwe a mamolecular: c52h74n16o15s2

Kulemera kwa maselo: 1227.37

Nainecs nambala: 238-68-8

Malo owiritsa: 1824.0 ± 65,0 ° C (Extrated)

Kuchulukitsa: 1.46 ± 0,1 g / cm3 (kulosera)

Malo amdima, malo amdima, malo ogulitsira, osungira -15 ° C.

Acidity coe:


Tsatanetsatane wazogulitsa

Matamba a malonda

Tsatanetsatane wazogulitsa

Dzina N- (N-(N-Glycyllcyl) Glycyl) -8-l-lysinevasopresten
Nambala ya cas 14636-12-5
Mawonekedwe a matope C52Hh74N16O15S2
Kulemera kwa maselo 1227.37
Nambala ya Einecs 238-68-8
Malo otentha 1824.0 ± 65.0 ° C (Extrated)
Kukula 1.46 ± 0,1 g / cm3 (kulosera)
Malo osungira Khalani m'malo amdima, m'mlengalenga, sungani mufiriji, pa -15 ° C.
Acidity zolimba (PKA) 9.90 ± 0,15 (Enet)

Mawuno

[N--Triglycyl-8-lysine] -vasopressin; 130: Pn: Wn: Wn: Wn: Wn: Sn: Pn: Pn: Wn: Sn: Pn: Wn: Wn: Wo2013207720720EEQUD: 17 1-triglycyl-8-lysinevalopresmin; N α-glycyl-glycyl-glycyl- [8-Lusty] -vasopressin; N α-glycyl-glycyl-lysine-vasopresten; NCY-Glycyllcylcylllllllllllllllllllllllllllllllll-vasopresten; NL-Gly-Gly-Gly-8-vasopresten; Terlipressin, terlipresresini, terlipresresna, terlipressenam.

Kaonekeswe

Terlipresressin, yemwe dzina lake la Denalo ndi Trigylylyunine vasopresten, ndi kukonzekera kwatsopano kwa vasopresten. Ndi mtundu wa prodrug, womwe umakhala wokha. Amachita ndi aminopliroptidase mu vivo phulusa pang'onopang'ono "kumasula" nthochi ya intsin vasopresnin atatsalira otsalira atatu a Grecyl ku n-termisus. Chifukwa chake, terlipressen amachita ngati malo osungira omwe amatulutsa lysine vasopresnin pamalo okhazikika.

Mphamvu ya pharlipraciol ya terliprestenin ndi mgwirizano wamitsempha yosalala ndipo imachepetsa kutuluka magazi mu meseji, ndulu, russis, etc.) Komabe, zingachepetsenso plasma mphamvu ya Renin, potero kuonjezera magazi a impso, kukonza ma aimpso ndikuwonjezera makodzo a hepatomenal syndrome. Terlipressentin pakadali pano mankhwala okhawo omwe angathandize kupulumuka odwala omwe ali ndi varcegel ya esophogel. Zinagwiritsidwa ntchito makamaka pamankhwala a varcel hemorrhage. Kuphatikiza apo, terlipressin yagwiritsidwanso ntchito mu chiwindi ndi impso. Mwambiri, mwina amatenga gawo labwino pakugwedezeka kogwirizana ndi kadisopulombolomary. Poyerekeza ndi Vosopressin, imakhala ndi zovuta zazitali, sizimayambitsa zovuta zoopsa, kuphatikizapo mafinya akuluakulu komanso zovuta zomwe zimagwiritsidwa ntchito mwamphamvu. Kupulumutsa ndi chithandizo cha odwala odwala kwambiri.


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