Dzina | N- (N-(N-Glycyllcyl) Glycyl) -8-l-lysinevasopresten |
Nambala ya cas | 14636-12-5 |
Mawonekedwe a matope | C52Hh74N16O15S2 |
Kulemera kwa maselo | 1227.37 |
Nambala ya Einecs | 238-68-8 |
Malo otentha | 1824.0 ± 65.0 ° C (Extrated) |
Kukula | 1.46 ± 0,1 g / cm3 (kulosera) |
Malo osungira | Khalani m'malo amdima, m'mlengalenga, sungani mufiriji, pa -15 ° C. |
Acidity zolimba | (PKA) 9.90 ± 0,15 (Enet) |
[N--Triglycyl-8-lysine] -vasopressin; 130: Pn: Wn: Wn: Wn: Wn: Sn: Pn: Pn: Wn: Sn: Pn: Wn: Wn: Wo2013207720720EEQUD: 17 1-triglycyl-8-lysinevalopresmin; N α-glycyl-glycyl-glycyl- [8-Lusty] -vasopressin; N α-glycyl-glycyl-lysine-vasopresten; NCY-Glycyllcylcylllllllllllllllllllllllllllllllll-vasopresten; NL-Gly-Gly-Gly-8-vasopresten; Terlipressin, terlipresresini, terlipresresna, terlipressenam.
Terlipresressin, yemwe dzina lake la Denalo ndi Trigylylyunine vasopresten, ndi kukonzekera kwatsopano kwa vasopresten. Ndi mtundu wa prodrug, womwe umakhala wokha. Amachita ndi aminopliroptidase mu vivo phulusa pang'onopang'ono "kumasula" nthochi ya intsin vasopresnin atatsalira otsalira atatu a Grecyl ku n-termisus. Chifukwa chake, terlipressen amachita ngati malo osungira omwe amatulutsa lysine vasopresnin pamalo okhazikika.
Mphamvu ya pharlipraciol ya terliprestenin ndi mgwirizano wamitsempha yosalala ndipo imachepetsa kutuluka magazi mu meseji, ndulu, russis, etc.) Komabe, zingachepetsenso plasma mphamvu ya Renin, potero kuonjezera magazi a impso, kukonza ma aimpso ndikuwonjezera makodzo a hepatomenal syndrome. Terlipressentin pakadali pano mankhwala okhawo omwe angathandize kupulumuka odwala omwe ali ndi varcegel ya esophogel. Zinagwiritsidwa ntchito makamaka pamankhwala a varcel hemorrhage. Kuphatikiza apo, terlipressin yagwiritsidwanso ntchito mu chiwindi ndi impso. Mwambiri, mwina amatenga gawo labwino pakugwedezeka kogwirizana ndi kadisopulombolomary. Poyerekeza ndi Vosopressin, imakhala ndi zovuta zazitali, sizimayambitsa zovuta zoopsa, kuphatikizapo mafinya akuluakulu komanso zovuta zomwe zimagwiritsidwa ntchito mwamphamvu. Kupulumutsa ndi chithandizo cha odwala odwala kwambiri.