Eptifibatide for Treatment of Acute Coronary Syndrome 188627-80-7
Tsatanetsatane wa Zamalonda
| Dzina | Eptifibatide |
| Nambala ya CAS | 188627-80-7 |
| Mapangidwe a maselo | Chithunzi cha C35H49N11O9S2 |
| Kulemera kwa maselo | 831.96 |
| Nambala ya EINECS | 641-366-7 |
| Kuchulukana | 1.60±0.1 g/cm3(Zonenedweratu) |
| Zosungirako | Amasindikizidwa mu chowuma, kusungidwa mufiriji, pansi pa -15 ° C |
Mawu ofanana ndi mawu
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6- (Aminoiminomethyl) -N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2) (DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein Antagonist
Etifibatide (integrilin) ndi buku la polypeptide platelet glycoprotein IIb/IIIa receptor antagonist, yomwe imalepheretsa kuphatikizika kwa mapulateleti ndi thrombosis mwa kuletsa njira yomaliza yophatikizira mapulateleti.Poyerekeza ndi monoclonal antibody abciximab, eptifibatide ili ndi mphamvu, yolunjika komanso yomangirira mwachindunji ku GPIIb/IIIa chifukwa cha kukhalapo kwa amino acid imodzi yokha - lysine m'malo mwa arginine.Choncho, ziyenera kukhala zabwino achire zotsatira interventional mankhwala pachimake coronary syndrome.Platelet glycoprotein IIb/IIIa receptor antagonist mankhwala apangidwa kwambiri, ndipo pakali pano pali mitundu ya 3 yokonzekera yomwe ingagwiritsidwe ntchito m'chipatala padziko lonse lapansi, abciximab, eptifibatide ndi tirofiban.).Palibe chidziwitso chochepa pakugwiritsa ntchito ma platelet glycoprotein GPIIb/IIIa receptor antagonists ku China, ndipo mankhwala omwe alipo amakhalanso ochepa kwambiri.Mankhwala amodzi okha, tirofiban hydrochloride, ali pamsika.Chifukwa chake, glycoprotein IIb yatsopano idapangidwa./ IIIa receptor antagonists ndizofunikira.Domestic eptifibatide ndi chinthu chotsanzira chopangidwa ndi Chengdu Sino Biological Products Co., Ltd.
Gulu
Gulu la Antiplatelet Aggregation Drugs
Antiplatelet aggregation mankhwala akhoza pafupifupi kugawidwa m'magulu atatu: 1. Cyclooxygenase-1 (COX-1) inhibitors, monga aspirin.2. Kuletsa kuphatikizika kwa mapulateleti opangidwa ndi adenosine diphosphate (ADP), monga clopidogrel, prasugrel, cangrelor, ticagrelor, etc. 3. Platelet glycoprotein Ⅱb / Ⅲa receptor antagonists, monga abciximab, eptifibatide, etc. prostaglandin EP3 receptor inhibitors, zigawo zamankhwala zomwe zangopangidwa kumene komanso zogwira mtima zochokera kumankhwala achi China.
