Peptide APIs
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MOTS-C
MOTS-C API imapangidwa pansi pamikhalidwe yolimba ngati ya GMP pogwiritsa ntchito ukadaulo wa solid phase peptide synthesis (SPPS) kuti iwonetsetse kuti imakhala yapamwamba kwambiri, yoyera kwambiri komanso yokhazikika pakufufuza komanso kugwiritsa ntchito mankhwala.
Zogulitsa:Kuyera ≥ 99% (kutsimikiziridwa ndi HPLC ndi LC-MS),
Endotoxin yotsika komanso zosungunulira zotsalira,
Zopangidwa molingana ndi ma protocol a ICH Q7 ndi GMP,
Itha kukwaniritsa kupanga kwakukulu, kuchokera pamagulu a R&D a milligram-level mpaka gram-level ndi malonda a kilogalamu. -
Ipamorelin
Ipamorelin API imakonzedwa ndi njira yapamwamba kwambiri **solid phase peptide synthesis process (SPPS)** ndipo imayesedwa kotheratu ndi kuyezetsa koyenera, koyenera kugwiritsa ntchito mapaipi oyambirira mu kafukufuku wa sayansi ndi chitukuko ndi makampani opanga mankhwala.
Zogulitsa zikuphatikiza:
Purity ≥99% (HPLC test)
Palibe endotoxin, zosungunulira zotsalira zochepa, kuipitsidwa kwa ayoni achitsulo otsika
Perekani zolemba zonse zamtundu wabwino: COA, lipoti la kukhazikika, kusanthula kwazinthu zonyansa, ndi zina.
Kupezeka kwa mulingo wa gramu ~ kilogalamu-level -
Pulegone
Pulegone ndi monoterpene ketone yopezeka mwachilengedwe yomwe imapezeka mumafuta ofunikira amitundu ya timbewu monga pennyroyal, spearmint, ndi peppermint. Amagwiritsidwa ntchito ngati zokometsera, chigawo cha fungo, komanso chapakatikati pakupanga mankhwala ndi mankhwala. Pulegone API yathu imapangidwa kudzera m'zigawo zoyeretsedwa komanso zoyeretsera kuti zitsimikizire chiyero chapamwamba, kusasinthika, komanso kutsata mfundo zoyenera zachitetezo ndi zabwino.
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Etelcalcetide
Etelcalcetide ndi mankhwala a peptide calcimimetic omwe amagwiritsidwa ntchito pochiza hyperparathyroidism (SHPT) kwa odwala omwe ali ndi matenda aakulu a impso (CKD) pa hemodialysis. Zimagwira ntchito poyambitsa calcium-sensing receptor (CaSR) pama cell a parathyroid, potero kutsitsa ma hormone a parathyroid (PTH) ndikuwongolera mineral metabolism. Etelcalcetide API yathu yoyera kwambiri imapangidwa kudzera mu solid-phase peptide synthesis (SPPS) pansi pamikhalidwe yogwirizana ndi GMP, yoyenera jekeseni.
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Bremelanotide
Bremelanotide ndi peptide yopangidwa ndi melanocortin receptor agonist yomwe imapangidwira kuchiza matenda a hypoactive sex chilakolako disorder (HSDD) mwa amayi omwe ali ndi premenopausal. Imachita poyambitsa MC4R m'katikati mwa mitsempha kuti ipititse patsogolo chilakolako chogonana komanso kudzutsidwa. Bremelanotide API yathu yoyera kwambiri imapangidwa kudzera mwa solid-phase peptide synthesis (SPPS) pansi pamiyezo yokhazikika, yoyenera jekeseni.
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Etelcalcetide Hydrochloride
Etelcalcetide Hydrochloride ndi peptide-based calcimimetic agent yomwe imagwiritsidwa ntchito pochiza hyperparathyroidism (SHPT) kwa odwala omwe ali ndi matenda a impso (CKD) pa hemodialysis. Zimagwira ntchito poyambitsa calcium-sensing receptors (CaSR) pa chithokomiro cha parathyroid, motero kuchepetsa kuchuluka kwa mahomoni a parathyroid (PTH) ndikuwongolera bwino kwa calcium-phosphate. Etelcalcetide API yathu imapangidwa kudzera mu kaphatikizidwe ka peptide yoyera kwambiri ndipo imagwirizana ndi miyezo yapadziko lonse lapansi yamankhwala obaya jakisoni.
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Desmopressin Acetate Kuchiza chapakati Diabetes Insipidus
Dzina: Desmopressin
Nambala ya CAS: 16679-58-6
Mapangidwe a maselo: C46H64N14O12S2
Kulemera kwa molekyulu: 1069.22
Nambala ya EINECS: 240-726-7
Kuzungulira kwachindunji: D25 +85.5 ± 2 ° (kuwerengera peptide yaulere)
Kachulukidwe: 1.56±0.1 g/cm3(Zonenedweratu)
Nambala ya RTECS: YW9000000
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Eptifibatide for Treatment of Acute Coronary Syndrome 188627-80-7
Dzina: Eptifibatide
Nambala ya CAS: 188627-80-7
Mulingo wa molekyulu: C35H49N11O9S2
Kulemera kwa molekyulu: 831.96
Nambala ya EINECS: 641-366-7
Kachulukidwe: 1.60±0.1 g/cm3(Zonenedweratu)
Malo osungira: Chosindikizidwa pouma, sungani mufiriji, pansi pa -15°C
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Terlipressin Acetate ya Esophageal Variceal Bleeding
Dzina: N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
Nambala ya CAS: 14636-12-5
Mapangidwe a maselo: C52H74N16O15S2
Kulemera kwa molekyulu: 1227.37
Nambala ya EINECS: 238-680-8
Malo otentha: 1824.0±65.0 °C (Zonenedweratu)
Kachulukidwe: 1.46±0.1 g/cm3(Zonenedweratu)
Malo osungira: Sungani pamalo amdima, m'malo opanda mpweya, Sungani mufiriji, pansi pa -15°C.
Acidity coefficient: (pKa) 9.90±0.15 (Zonenedweratu)
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Teriparatide Acetate API for Osteoporosis CAS NO.52232-67-4
Teriparatide ndi kupanga 34-peptide, 1-34 amino acid chidutswa cha munthu parathyroid timadzi PTH, amene ndi biologically yogwira N-terminal dera 84 amino zidulo endogenous parathyroid hormone PTH. The immunological and biological properties of this product is the same same as the endogenous parathyroid hormone PTH ndi bovine parathyroid hormone PTH (bPTH).
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Atosiban Acetate Amagwiritsidwa Ntchito Pakubadwa Kwapanthawi Yasanakwane
Dzina: Atosiban
Nambala ya CAS: 90779-69-4
Mapangidwe a maselo: C43H67N11O12S2
Kulemera kwa molekyulu: 994.19
Nambala ya EINECS: 806-815-5
Malo otentha: 1469.0±65.0 °C (Zonenedweratu)
Kachulukidwe: 1.254±0.06 g/cm3(Zonenedweratu)
Zosungirako: -20°C
Kusungunuka: H2O: ≤100 mg/mL
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Carbetocin Kupewa Kutsekeka kwa Uterine ndi Kutaya Kutuluka kwa Postpartum
Dzina: CARBETOCIN
Nambala ya CAS: 37025-55-1
Mapangidwe a maselo: C45H69N11O12S
Kulemera kwa molekyulu: 988.17
Nambala ya EINECS: 253-312-6
Kuzungulira kwachindunji: D -69.0° (c = 0.25 mu 1M acetic acid)
Malo otentha: 1477.9±65.0 °C (Zonenedweratu)
Kachulukidwe: 1.218±0.06 g/cm3(Zonenedweratu)
Kusungirako: -15°C
Fomu: ufa