Desmopressin Acetate Kuchiza chapakati Diabetes Insipidus
Tsatanetsatane wa Zamalonda
| Dzina | Desmopressin |
| Nambala ya CAS | 16679-58-6 |
| Mapangidwe a maselo | Zithunzi za C46H64N14O12S2 |
| Kulemera kwa maselo | 1069.22 |
| Nambala ya EINECS | 240-726-7 |
| Kuzungulira kwachindunji | D25 +85.5 ± 2 ° (yowerengera peptide yaulere) |
| Kuchulukana | 1.56±0.1 g/cm3(Zonenedweratu) |
| RTECS No. | YW9000000 |
| Zosungirako | Sungani pa 0°C |
| Kusungunuka | H2O: soluble20mg/mL, zomveka, zopanda mtundu |
| Acidity coefficient | (pKa) 9.90±0.15 (Zonenedweratu) |
Mawu ofanana ndi mawu
MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2;MINIRIN;[DEAMINO1, DARG8] VASOPRESSIN;[DEAMINO-CYS1, D-ARG8]-VASOPRESSIN;DDAVP, MUNTHU;DESMOPRESSIN;DESMOPRESSIN, MUNTHU;DESAMINO-[D-ARG8] VASOPRESSIN
Zizindikiro
(1) Chithandizo cha matenda a shuga a insipidus.Pambuyo mankhwala akhoza kuchepetsa mkodzo excretion, kuchepetsa mkodzo pafupipafupi ndi kuchepetsa nocturia.
(2) Chithandizo cha nocturnal enuresis (odwala azaka 5 kapena kuposerapo).
(3) Yesani aimpso mkodzo ndende ntchito, ndi kuchita masiyanitsidwe matenda aimpso ntchito.
(4) Kwa hemophilia ndi matenda ena otaya magazi, mankhwalawa amatha kufupikitsa nthawi yotaya magazi ndikuletsa kutuluka kwa magazi.Ikhoza kuchepetsa kutayika kwa magazi kwa intraoperative ndi kutuluka kwa postoperative;makamaka mogwirizana ndi kuthamanga kwa magazi koyendetsedwa bwino panthawi ya opaleshoni, kungathe kuchepetsa kutuluka kwa magazi kuchokera ku njira zosiyanasiyana, ndi kuchepetsa kutuluka kwa postoperative, komwe kungathandize kwambiri kuteteza magazi.
Chithandizo cha matenda a shuga insipidus
Matenda a shuga a insipidus makamaka ndi vuto la kagayidwe ka madzi komwe kumadziwika ndi kuchuluka kwa mkodzo, polydipsia, hypoosmolarity, ndi hypernatremia.Kuperewera kwapang'ono kapena kwathunthu kwa vasopressin (central diabetes insipidus), kapena aimpso kusakwanira kwa vasopressin (nephrogenic shuga insipidus) kumatha kuyambitsa.Kachipatala, matenda a shuga insipidus ndi ofanana ndi polydipsia yoyamba, mkhalidwe womwe kumwa kwambiri madzimadzi kumachitika chifukwa cha kusagwira bwino ntchito kwa njira zowongolera kapena ludzu losazolowereka.Mosiyana ndi polydipsia yoyamba, kuchuluka kwa madzi kwa odwala omwe ali ndi matenda a shuga insipidus ndikofanana ndi kusintha kwa kuthamanga kwa osmotic kapena kuchuluka kwa magazi.
