Vancomycin ndi mankhwala a glycopeptide omwe amagwiritsidwa ntchito ngati antibacterial
Tsatanetsatane wa Zamalonda
| Dzina | Vancomycin |
| Nambala ya CAS | 1404-90-6 |
| Mapangidwe a maselo | C66H75Cl2N9O24 |
| Kulemera kwa maselo | 1449.25 |
| Nambala ya EINECS | 215-772-6 |
| Kuchulukana | 1.2882 (kuyerekeza movutikira) |
| Refractive index | 1.7350 (chiyerekezo) |
| Zosungirako | Osindikizidwa mu youma, 2-8 ° C |
Mawu ofanana ndi mawu
Vancomycin(mchere wapansi ndi/orunspecified);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR) -3-(2-Amino-2-oxoethyl)-44-[[2-O-( 3-amino-2,3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy] -10,19-dichloro-2,3,4,5, 6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-[[(2R) -4-methChemicalbookyl-2-(methylamino) )-1-oxopentyl]amino]-2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno -1H, 16H- [1,6,9] oxadiazacyclohexadecino [4,5-m] [10,2,16] benzoxadiazacyclotetracosine-26-carboxylicacid.
Kufotokozera
Vancomycin ndi mankhwala a glycopeptide.Limagwirira ake zochita ndi kumanga ndi mkulu kuyanjana kwa alanylalanine pa poly-terminal mapeto a kalambulabwalo peptide wa tcheru bakiteriya cell khoma, kutsekereza synthesis wa macromolecular peptidoglycan kuti amapanga bakiteriya selo khoma, chifukwa Kuwonongeka kwa selo. khoma limapha mabakiteriya.Vancomycin ndi othandiza pa matenda oopsa omwe amayamba chifukwa cha mabakiteriya a gram-positive, makamaka omwe amayamba ndi Staphylococcus aureus wosamva methicillin, Staphylococcus epidermidis, ndi Enterococcus omwe samva maantibayotiki ena kapena osagwira ntchito bwino.
Zizindikiro
Zimangokhala ndi matenda opatsirana omwe amayamba chifukwa cha methicillin-resistant Staphylococcus aureus (MRSA) ndi matenda a m'mimba ndi matenda opatsirana chifukwa cha Clostridium difficile;Penicillin-matupi odwala sangagwiritse ntchito penicillin kapena cephalosporins odwala kwambiri staphylococcal matenda, kapena kwambiri staphylococcal matenda amene alephera kulabadira pamwamba mankhwala, vancomycin angagwiritsidwe ntchito.Izi mankhwala amagwiritsidwanso ntchito zochizira Enterococcus endocarditis ndi Corynebacterium (Diphtheria-ngati) endocarditis anthu matupi awo sagwirizana penicillin.Chithandizo cha staphylococcus-induced arteriovenous shunt matenda mu hemodialysis odwala sagwirizana ndi penicillin ndi sanali matupi awo sagwirizana penicillin.
