Liraglitide Anti-Dishuis wa Shuga wa Shuga Magazi Shuga Cas No.204656-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-20-25

Matenda a shuga 2

Liraglitide amawongolera shuga wamagazi. Imachepetsa hyperglycemia yokhudzana ndi chakudya (kwa maola 24 pambuyo pokonza kachilombo (kokha) powonjezera insulin (kokha) ikafunikira powonjezera milingo ya shuga, ndikuchepetsa kuthira cha m'mimba, ndikuphwanya Glundial Glucagon.
Ndioyenera odwala omwe shuga yemwe shuga yemwe amagazi sakawongoleredwa bwino pambuyo polekerera muyeso wa metformin kapena sulfonylurea yokha. Amagwiritsidwa ntchito kuphatikiza ndi metformin kapena sulfonylureas.
Imagwira ntchito modalira mtundu wa glucose, kutanthauza kuti zimalimbikitsa chinsinsi cha insulin pokhapokha ngati milingo yamagazi ya shuga ndiyokwera kuposa nthawi zonse, kupewa ". Zotsatira zake, zimawonetsa chiopsezo cha hypoglycemia.
Ili ndi mwayi woletsa Apoptosis ndikusinthanso kwa beta (kuwoneka mu kafukufuku wa nyama).
Zimachepetsa kulakalaka ndipo zimalepheretsa kunenepa thupi, monga tikuwonetsera mu phwendeni mutu motsutsana ndi glidepride.

Zochita za pharmacological

Liraglitdide ndi gawo limodzi lokhala ndi 97% yotsatizana ndi Arplogy ya Alp-1, yomwe imathamangitsidwa ndikuyambitsa vomerezani-1. Kulandila kwa GLP-1 ndi chandamale cha General GLP-1, chisoti cha Engrenous Exretonin chomwe chimalimbikitsa chinsinsi cha slucose-insulin kuchokera ku Pancreatic β. Mosiyana ndi mtundu wa genp-1, pharmacokinetic ndi pharmacondnamic mbiri ya Liraglutiside mwa anthu ndi oyenera kanthawi koyambira. Pambuyo pa jakisoni wokhazikika, njira yake yochitira nthawi yayitali imaphatikizapo: kudziyanjana komwe kumachepetsa kuyamwa; kumanga albumin; Enzyme yokhazikika mokha ndikukhala ndi plasma theka-moyo.

Ntchito ya Liraglitide imalumikizidwa ndi kuyanjana kwake mwachindunji ndi yolandilidwa ndi Glop-1, zomwe zidapangitsa kuti pakhale cyclica adenosine monopthosphate (ndende). Liraglutide amalimbikitsa insulin insulition mu mtundu wa glucose-mtundu wa staction, pomwe amachepetsa chikopa chochuluka cha glucagon mu mawonekedwe a glucose.

Chifukwa chake, magazi a magazi akamakwera, insulin kalensidwe amalimbikitsidwa, pomwe glucagon kafukufuku wa Glucan amalephereka. Mosiyana ndi izi, liraglutide amachepetsa intulin kubisalira nthawi ya hypoglycemia popanda kukhumudwitsa a glucagon. Makina a hypoglycemic a liraglutide umaphatikizaponso kutalika kochepa kwa nthawi yonyansa ya chapamimba. Liraglutide amachepetsa kulemera kwa thupi ndi mafuta thupi pochepetsa njala komanso mphamvu.