Eptifibatide for Treatment of Acute Coronary Syndrome 188627-80-7
Tsatanetsatane wa Zamalonda
| Dzina | Eptifibatide |
| Nambala ya CAS | 188627-80-7 |
| Molecular formula | Chithunzi cha C35H49N11O9S2 |
| Kulemera kwa maselo | 831.96 |
| Nambala ya EINECS | 641-366-7 |
| Kuchulukana | 1.60±0.1 g/cm3(Zonenedweratu) |
| Zosungirako | Amasindikizidwa mu zouma, kusungidwa mufiriji, pansi pa -15 ° C |
Mawu ofanana ndi mawu
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoimi nomethyl) -N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteineamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein Antagonist
Etifibatide (integrilin) ndi buku la polypeptide platelet glycoprotein IIb/IIIa receptor antagonist, yomwe imalepheretsa kuphatikizika kwa mapulateleti ndi thrombosis mwa kuletsa njira yomaliza yophatikizira mapulateleti. Poyerekeza ndi monoclonal antibody abciximab, eptifibatide ili ndi mphamvu, yolunjika komanso yomangirira mwachindunji ku GPIIb/IIIa chifukwa cha kukhalapo kwa amino acid imodzi yokha - lysine m'malo mwa arginine. Choncho, ziyenera kukhala zabwino achire zotsatira interventional mankhwala pachimake coronary syndrome. Platelet glycoprotein IIb/IIIa receptor antagonist mankhwala apangidwa kwambiri, ndipo pakali pano pali mitundu ya 3 yokonzekera yomwe ingagwiritsidwe ntchito m'chipatala padziko lonse lapansi, abciximab, eptifibatide ndi tirofiban. ). Palibe chidziwitso chochepa pakugwiritsa ntchito ma platelet glycoprotein GPIIb/IIIa receptor antagonists ku China, ndipo mankhwala omwe alipo nawonso ndi ochepa kwambiri. Mankhwala amodzi okha, tirofiban hydrochloride, ali pamsika. Chifukwa chake, mapulateleti atsopano a glycoprotein IIb adapangidwa. / IIIa receptor antagonists ndizofunikira. Domestic eptifibatide ndi chinthu chotsanzira chopangidwa ndi Chengdu Sino Biological Products Co., Ltd.
Gulu
Gulu la Antiplatelet Aggregation Drugs
Antiplatelet aggregation mankhwala akhoza pafupifupi kugawidwa m'magulu atatu: 1. Cyclooxygenase-1 (COX-1) inhibitors, monga aspirin. 2. Kuletsa kuphatikizika kwa mapulateleti opangidwa ndi adenosine diphosphate (ADP), monga clopidogrel, prasugrel, cangrelor, ticagrelor, etc. 3. Platelet glycoprotein Ⅱb / Ⅲa receptor antagonists, monga abciximab, eptifibatide, etc. zoletsa, zigawo zamankhwala zomwe zangopangidwa kumene komanso zogwira mtima zochokera kumankhwala achi China.
