Paclitaxel 33069-62-4-4-4-4-4-4-4-4-5-4
Tsatanetsatane wazogulitsa
| Dzina | PCLTAXELE |
| Nambala ya cas | 33069-62-4 |
| Mawonekedwe a matope | C47h51N |
| Kulemera kwa maselo | 853.92 |
| Nambala ya Einecs | 608-826-9 |
| Malo otentha | 774.66 ° C (Extrated) |
| Kukula | 0.200 |
| Kusunga | Osindikizidwa muuma, sitolo mufiriji, 2-8 ° C |
| Fumu | Pawuda |
| Mtundu | Oyera |
| Kupakila | Pe thumba + aluminium thumba |
Mawuno
Paclitaxel HCL; Paclitaxel (chilengedwe); Paclitaxelx; N-Benzyl-Bea-PHLASTITAXEER, Mitundu ya Thnitaxel; Paclitaxel
Pharmacological zotsatira
Kaonekeswe
Paclitaxel ndi a monomeric diterpenoid yochokera ku khungwa la chomera cham'mimba. Malo ofufuza a Inotope adawonetsa kuti PCLTITAXEXEXEXE SOROR kopendekera microtubales ndipo sanayankhe ndi tubulin yopanda kuponyera. Maselo atawonekera ku Paclitaxel, ambiri a microtubules adzasonkhanitsidwa m'maselo. Kuchuluka kwa microtubales awa kumasokoneza magawo osiyanasiyana a maselo, makamaka magawano a cellotive amasiya gawo la mitotic ndikukhomerera ma cell a cell. Kupyola ⅱ-ⅲ Kafukufuku wazachipatala, Paclitaxel makamaka ndi khansa ya Ovariya ndi khansa ya m'mapapo, komanso khansa yapamtunda, mutu ndi khosi ndi chotupa chaubongo.
Umboni
Zimakhala ndi zotsatira zabwino mankhwalawa a khansa ya Ovariya ndi platinamu ndi khansa inanso ya Ovariya ndi khansa ya m'mawere. Khansa, chapamwamba chapamwamba cha khansa yam'mimba, khungu laling'ono komanso losakhala laling'ono la ma cell m'mapapo ali ndi chiyembekezo chabwino.
Ntchito
Gwiritsani 1: Boma lotupa la anti-Spectrom la khansa ya Ovariya, khansa ya m'mawere, etc.
Gwiritsani ntchito 2: bora otupa a anti-spertrom zotupa zochizira khansa ya ovariya, khansa ya m'mawere ndi matenda ena.
Gwiritsani ntchito 3: mankhwala a antitumor. Zochizira khansa ya m'mawere ndi khansa ya ovaria. Bokosi lotupa la anti-lotupa limapangitsa khansa ya ovariya, khansa ya m'mawere ndi matenda ena.
Gwiritsani 4: Ntchito yogwira ntchito yotsutsa-chotupa; Amamangiriza ku gawo la N-termial a β-blilin, amalimbikitsa Statulmeule microtubule, amaletsa magawano wamba a cell ndi misampha mu gawo la g2 / m mu gawo la cell.
Gwiritsani ntchito 5: Wotsutsa-Microtubule mankhwala, kulepheretsa deolmerrization polimbikitsa polymerization polymerization, kukhazikika ku babalin, ndikulepheretsa foni ya cell.
