Chondroitin Sulfate Yochizira Matenda a Mtima, Matenda a Nyamakazi ndi Machiritso a Corneal Wounds Purity 98% Chithunzi Chowonetsedwa

Chondroitin sulfate pochiza matenda a mtima, nyamakazi ndi machiritso a Corneal Wounds Purity 98%

Kufotokozera Kwachidule:

Nambala ya CAS: 9007-28-7

Mapangidwe a maselo: C13H21NO15S

Kulemera kwa molekyulu: 463.36854

Nambala ya EINECS: 232-696-9

Fomu: ufa

Mtundu: Woyera mpaka Woyera

Kusungunuka m’madzi: Kusungunuka m’madzi

Chiyero: 98%

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Tsatanetsatane wa Zamalonda

Dzina	Chondroitin sulphate
Nambala ya CAS	9007-28-7
Molecular formula	Chithunzi cha C13H21NO15S
Kulemera kwa maselo	463.36854
Nambala ya EINECS	232-696-9
Kusungunuka kwamadzi	Zosungunuka m'madzi
Chiyero	98%
Kusungirako	Sungani pa kutentha wokhazikika
Fomu	Ufa
Mtundu	Zoyera mpaka zoyera
Kulongedza	Chikwama cha PE + Chikwama cha Aluminium

Mawu ofanana ndi mawu

poly-1 (2/3)-n-acetyl-2-amino-2-deoxy-3-o-beta-d-glucopyranurosyl-4-(6)sulfonyl-d-galactose;chondroitinpoly sulphate;chondroitin sulphates;chondroiti sulfuricacid;chondroitin sulfuric acid;chonsurid;CSO;(5ξ) -2-(Carboxyamino) -2-deoxy-3-O-β-D-glucopyranuronosyl-4-O-sulfo-α-L-arabino-hexopyranose

Pharmacological Effect

Kufotokozera

Chondroitinsulfate (CS) ndi acidic mucopolysaccharide yotengedwa ndikuyeretsedwa ku minofu ya nyama.Chondroitin sulfate ili ndi mapangidwe osiyanasiyana monga A, C, D, E, H ndi K. Chondroitin sulfate m'chilengedwe imapezeka kwambiri mu chichereŵechereŵe chanyama, fupa la pakhosi, fupa lamphuno (41% mu nkhumba), ng'ombe, septum ya akavalo ndi trachea (yokhala ndi 36% mpaka 39%), minofu ina monga mafupa a mwendo, mitsempha, khungu, cornea, ndi zina zotero.Zomwe zili mu cartilage ya nsomba ndizolemera kwambiri, monga 50% mpaka 60% mu mafupa a shark, ndi zochepa kwambiri mu minofu yolumikizana.

Pakuti mitima atherosclerotic matenda, kuchuluka lipids magazi ndi mafuta m`thupi, arteriosclerosis, angina pectoris, m`mnyewa wamtima ischemia, m`mnyewa wamtima infarction, etc. odwala matenda a mtima.

Pharmacological Action

Rapamycin (RAPA) ili ndi zotsatira zofanana ndi FK506.M'mayesero ambiri azachipatala, zotsatira zake zidapezeka kuti zimadalira mlingo komanso zosinthika, ndipo RAPA pamankhwala ochizira sanapezeke kuti ali ndi nephrotoxicity yayikulu komanso palibe gingival hyperplasia.Chachikulu poizoni ndi zotsatira zake monga: mutu, nseru, chizungulire, nosebleeds, ndi ululu m`malo olumikizirana mafupa.Zachilengedwe za labotale ndi monga: thrombocytopenia, leukopenia, hemoglobin yotsika, hypertriglyceridemia, hypercholesterolemia, hyperglycemia, kuchuluka kwa michere ya chiwindi (SGOT, SGPT), kuchuluka kwa lactate dehydrogenase, hypokalemia, Hypomagnesemia, etc. Miyezo ya phosphate ya plasma imaganiziridwa kuti ndi nthawi yayitali ya phosphate excretion kuchokera ku impso zobzalidwa ndi RAPA-based immunosuppressive therapy.Mofanana ndi ma immunosuppressants ena, RAPA ili ndi mwayi wowonjezereka wotenga matenda, ndi chizolowezi chowonjezeka makamaka chibayo, koma kupezeka kwa matenda ena ongotengera mwayi sikusiyana kwambiri ndi CsA.

Zotsatira za Toxicological

Chondroitin sulphate amapezeka kwambiri m'matumbo a anthu ndi nyama.Kukonzekera kwamankhwala kumakhala ndi ma isomers awiri a chondroitin sulfate A ndi chondroitin sulfate C, ndipo zomwe zili mu chondroitin sulfate mu chichereŵechereŵe cha nyama zamitundu yosiyanasiyana ndi mibadwo ndizosiyana.Zotsatira zake zamankhwala ndi izi: chondroitin sulfate imatha kuchotsa lipids ndi lipoproteins m'magazi, kuchotsa cholesterol m'mitsempha yamagazi kuzungulira mtima, kuteteza ndi kuchiza atherosclerosis, ndikuwonjezera kutembenuka kwa lipids ndi mafuta acids m'maselo.Chondroitin sulphate amatha kuteteza ndi kuchiza matenda a mtima.Ili ndi anti-atherosulinosis ndi anti-atherogenic plaque mapangidwe zotsatira pazoyeserera za arteriosclerosis;kumawonjezera nthambi zam'mitsempha kapena kufalikira kwa atherosulinosis, ndipo zimatha kufulumizitsa kuyesa kwa atherosulinosis kapena embolism.Machiritso, kusinthika ndi kukonzanso kwa myocardial necrosis kapena kuchepa.Ikhoza kuonjezera biosynthesis ya cell messenger ribonucleic acid (mRNA) ndi deoxyribonucleic acid (DNA) ndipo imakhala ndi zotsatira zolimbikitsa kagayidwe ka maselo.Low anticoagulant ntchito.Chondroitin sulphate ali zolimbitsa anticoagulant kwenikweni, ndipo aliyense 1 mg wa chondroitin sulfate A ndi lofanana ndi anticoagulant ntchito ya 0,45U wa heparin.Ntchito ya anticoagulant iyi sidalira antithrombin III kuti igwire ntchito yake, imatha kuchita ntchito ya anticoagulant kudzera mu dongosolo la fibrinogen.Chondroitin sulphate imakhalanso ndi anti-yotupa, imathandizira machiritso a bala komanso anti-chotupa zotsatira.

Zam'mbuyo: Rapamycin Ndi Mankhwala Osokoneza Bongo, Anti-cancer ndi Anti-kukalamba

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