ndi China Paclitaxel 33069-62-4 Anti-chotupa Botanical Medicine for Ovarian Cancer, Factory Cancer ya m'mawere ndi opanga |Gentolex
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Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine ya Ovarian Cancer, Khansa ya M'mawere Yowonetsedwa Chithunzi
  • Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine ya Ovarian Cancer, Cancer ya M'mawere
  • Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine ya Ovarian Cancer, Cancer ya M'mawere

Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine ya Ovarian Cancer, Cancer ya M'mawere

Kufotokozera Kwachidule:

Malo osungunuka: 213 °C

Malo otentha: 774.66°C (kuyerekeza movutikira)

Kuzungulira kwapadera: D20 -49°(methanol)

Kachulukidwe: 1.0352 (kuyerekeza movutikira)

Pothirira: 9°C

Kusungirako: 2-8°C

Fomu: ufa

Acidity coefficient: 11.90±0.20 (Zonenedweratu)

Mtundu: Woyera


Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Tsatanetsatane wa Zamalonda

Dzina Paclitaxel
Nambala ya CAS 33069-62-4
Molecular formula C47H51NO14
Kulemera kwa maselo 853.92
Nambala ya EINECS 608-826-9
Boiling Point 774.66°C (Zonenedweratu)
Kuchulukana 0.200
Mkhalidwe wosungira Zosindikizidwa mu zouma, Sungani mufiriji, 2-8°C
Fomu Ufa
Mtundu Choyera
Kulongedza Chikwama cha PE + Chikwama cha Aluminium

Mawu ofanana ndi mawu

Paclitaxel HCL;Paclitaxel(natural crude);Paclitaxelx;N-BENZYL-BETA-PHENYLISOSERINE ESTER;PACLITAXEL, TAXUS BREVIFOLIA;PACLITAXEL, TAXUS SPECIES;PACLITAXOL;PACLITAXEL

Pharmacological Effect

Kufotokozera

Paclitaxel ndi monomeric diterpenoid yotengedwa ku khungwa lachilengedwe la mankhwala a Taxus.Kufufuza kwa Isotope kunawonetsa kuti paclitaxel amangomanga ma microtubules opangidwa ndi polymerized ndipo sanachitepo ndi ma tubulin dimers opanda polymerized.Maselo atawonetsedwa ndi paclitaxel, ma microtubules ambiri adzasonkhanitsidwa m'maselo.Kuchuluka kwa ma microtubuleswa kumasokoneza ntchito zosiyanasiyana za maselo, makamaka magawano a cell amasiya mu gawo la mitotic ndikuletsa kugawanika kwa maselo.Kupyolera mu kafukufuku wachipatala wa Ⅱ-Ⅲ, paclitaxel ndiyoyenera kwambiri ku khansa ya m'mawere ndi khansa ya m'mawere, komanso imakhala ndi zotsatira zochizira khansa ya m'mapapo, khansara ya colorectal, melanoma, khansa ya mutu ndi khosi, lymphoma ndi chotupa cha muubongo.

 

Zizindikiro

Iwo ali ndi zotsatira zabwino pa matenda a khansa yamchiberekero ndi platinamu ndi zina refractory yamchiberekero khansa ndi khansa ya m'mawere.Khansara, khansa ya m'mimba yam'mimba, maselo ang'onoang'ono ndi khansa ya m'mapapo yomwe si yaing'ono imakhala ndi maonekedwe abwino.

 

Zogwiritsa

Gwiritsani ntchito 1: Broad-spectrum anti-tumor botanicals a khansa ya ovarian, khansa ya m'mawere, ndi zina.

Gwiritsani ntchito 2: botanicals anti-chotupa chachikulu pochiza khansa ya m'mawere, khansa ya m'mawere ndi matenda ena.

Gwiritsani ntchito 3: Mankhwala oletsa antitumor.Zochizira metastatic khansa ya m'mawere ndi metastatic ovarian khansa.Broad-spectrum anti-tumor botanicals pochiza khansa ya m'mawere, khansa ya m'mawere ndi matenda ena.

Gwiritsani ntchito 4: Mankhwala othandizira anti-chotupa;imamangiriza ku dera la N-terminal la β-tubulin, imalimbikitsa ma microtubule okhazikika kwambiri, amatsutsa depolymerization, amalepheretsa kugawanika kwa maselo ndi misampha mu gawo la G2 / M la selo.

Gwiritsani ntchito 5: Mankhwala oletsa tizilombo toyambitsa matenda, oletsa kutulutsa madzi polimbikitsa tubulin polymerization, kusunga kukhazikika kwa tubulin, ndi kuletsa ma cell mitosis.

 

 

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