Leuprorelin Acetate amawongolera kusungidwa kwa mahomoni a gonadal
Tsatanetsatane wazogulitsa
| Dzina | Leuprorelin |
| Nambala ya cas | 5371-56-0 |
| Mawonekedwe a matope | C59h84N16O12 |
| Kulemera kwa maselo | 1209.4 |
| Nambala ya Einecs | 633-995-9 |
| Kuzungulira kwina | D25 -31.7 ° (C = 1 mu 1% acetic acid) |
| Kukula | 1.44 ± 0,1 g / cm3 (kulosera) |
| Kusunga | -15 ° C |
| Fumu | Poyera |
| Acidity zolimba | (PKA) 9.82 ± 0.15 (adaloseredwa) |
| Madzi osungunuka | Sungunuka m'madzi ku 1mg / ml |
Mawuno
LH-Rhleuplide; Leaploride; Leupridede (Munthu); LeaprorelingLin (Pro-Gly10, D-Leu6, Pro -Nat9) -Lutenunghormone-makwereromone;
Pharmacological zotsatira
Leuploride, preserin, triparelin, ndi Nagarelin ndi mankhwala angapo omwe nthawi zambiri amagwiritsidwa ntchito pochiritsa khansa ya premenisal ndi khansa ya prostate. . Ndiye kuti, Gonadotropin yomwe idasungidwa ndi PiriothAd imachepera, yomwe imayambitsa kuchepa kwakukulu mu mahowo ogonana omwe amatulutsidwa ndi ovary.
Leiplotride ndi gonadotropin-bromone (gnrh) analog, peptide wopangidwa ndi 9 amino acid. Izi zimatha kulepheretsa ntchito ya plasaitary-gonadal, kukana kwa ma promolytic Gyrh receptor kuposa gnrh, komanso ntchito yolimbikitsa kumasulidwa kwa mahote mahone (LH) nthawi 20 ya GNRH. Ilinso ndi mphamvu yolimba pa pituitary-gonad ntchito kuposa gnrh. Mu gawo loyamba la chithandizo, follicle yolimbikitsa mahone (fsh), LH, estrogen kapena ma alrogen atha kwakanthawi, kenako Matenda ogonana (monga khansa ya prostate, endometriosis, etc.) kukhala ndi achire.
Pakadali pano, mchere wa leuptide wa Leuploride amagwiritsidwa ntchito makamaka pachipatala, chifukwa magwiridwe antchito a Leuptride amakhala okhazikika kutentha kwa firiji. Madzimadzi amayenera kutayidwa. Itha kugwiritsidwa ntchito popereka mankhwala ochizira matenda a perometrinosis ndi uterine fibrouid, khansa ya promenoopasal, ndi khansa yogwira ntchito yogwiritsira ntchito mankhwala osokoneza bongo. Itha kugwiritsidwanso ntchito ngati njira yosinthira isanayambe, yomwe imatha kuwonda edma, muchepetse Edma, ndikuchepetsa zovuta za opaleshoni.
