Dzina | Ganirelix acetate |
Nambala ya cas | 12324-29-7 |
Mawonekedwe a matope | C80h113333O13 |
Kulemera kwa maselo | 1570.34 |
AC-DCPA-DPAAL-DPAAL-DAR-DHR-DHAR (et2) - har (et)-et2) - ganirelixum; Ganirelix; Ginorelix Acetate USP / EP /
Ganirelix ndi wopanga detiptive dictoume, ndi mchere wake wa acetate, ganirelix acetate ndi gonadotropin-mahormone (gnrh) yoyeserera. Amino acid ndi awa: AC-D-4CPA-D-3Par-D-homo-homorg (9,10-ng2) -pro-da. Makamaka achipatala, imagwiritsidwa ntchito mwa azimayi omwe amathandizidwa ndi makina obala a Ovarian kuti ateteze zotupa za mahomoni asanakwane ndikuthana ndi mavuto achabechabe chifukwa cha izi. Mankhwalawa ali ndi mawonekedwe a zovuta zochepa, kuchuluka kwa pakati komanso nthawi yochepa kwambiri komanso nthawi yayitali yothandizira, ndipo ali ndi zabwino zambiri poyerekeza ndi mankhwala ofananira ndi mankhwala omwe ali pachipatala.
Kumasulidwa kwa Gonadotropin-Kumasulira mahomoni (gnrh) kumalimbikitsa kaphatikizidwe ndi katulutsidwe ka lh ndi fsh. Makina a LH amatulutsa mkati mwa ma mochedwa a follicular ndi pafupifupi 1 pa ola limodzi. Izi zimawonekera mu sikuti ku seram lh. Pakati pa kusamba, kumasulidwa kwakukulu kwa GNRH kumapangitsa kuchulukitsa kwa LH. Midmentrum ya LH imayambitsa mayankho angapo olimbitsa thupi, kuphatikiza: Ovulation, kuyambiranso kwa othandizira, ndi mapangidwe a Corpus Luteum. Kupanga kwa Corpus luteum kumayambitsa kuchuluka kwa seramu kuti uwuke, pomwe ma estradiol agwera. Ganirelix Acetate ndi gnrh yolimbana ndi mpikisano wa gnrh receptors pa Pileadarrophyrophs ndi njira zosinthira. Zimatulutsa mofulumira, zotchinga zotchinga za Gonadotropin katulutsidwe. Zotsatira za Ganirelix Acetate pa Pileather Lh secretion inali yamphamvu kuposa izi pa FSH. Ginirelix Acetate adalephera kuyika koyamba kwa Endotototropins, mogwirizana ndi mtundu wantissississississississississississississississississism. Kubwezeretsa kwathunthu kwa mbiatatury lh ndi ma flash milingo idachitika mkati mwa maola 48 pambuyo pa ganirelix pambuyo poti adasiya.