Sildenafil Citrate amathandizira Ectile Dysfunction 171599-83-0

Zochita za pharmacological
Sildenafil Citrate ndi njira yosankha ma 5-phrosphodesteanthula yolimbikitsa Nitric Nationadine, ma purcosphar, omwe ali ndi vuto la m'mimba, omwe adakumana ndi vuto lolimba poletsa ku cyccasphate. Kuphatikiza pa kufalikira mwachindunji kwa mitsempha yamagazi, imathanso kupewa kapena kusintha mavositala.

Mankhwala othandizira ndi mapulogalamu
Sildenafil Citrate, dzina la malonda Viagre, lomwe limadziwika kuti viagra, ndi a cgglic crophdodiesphate (CGEPICT PHOSPODODISTORTE (PDEPICT PHOSPODER) Eribodies omwe amatha kukulitsa masentimita. Sildenafil citrate amatha kukulitsa zotsatira za nitric oxide (Ayi) poletsa mtundu wa phosphoderiessies yomwe iomphoosphase monopthosphate (CGMP) mu Corpos Cavernosum. Onjezani kuchuluka kwa CGUP mu Corpus Cavertum, pumulani minofu yosalala mu hantpus cavertundum, kuwonjezera magazi, kuwonjezera magazini, nthawi yayitali yopanga. Kwa odwala omwe ali ndi vuto lofunikira. Akuluakulu amatenga kamka 50 nthawi iliyonse, mpaka 1 nthawi patsiku, ndipo amagwiritsa ntchito pofika ola limodzi musanayambe kugonana. Kuchuluka kwakukulu ndi 0.1g nthawi iliyonse.

Mu viva maphunziro
Agalu osilira, matenda a Sernafil Citrate zowonjezera penile. Sildenafil citrate Boamomoylchoylculaylchine-yolimbikitsidwa ndipo adaletsa mapangidwe a superoxide mu canroxide minyewa ya akalulu. Mu Sprague-Dawley makoswe, SPEENLEFIl amasintha ntchito ya erectile, modzitengera, ndikuchira kwa ma exmail kumachitika patsiku la 20 mg / kg patsiku. Mu sprague-dawley makoswe, makonzedwe a ku Sildenafil adayambitsa minofu ya minofu yosinthira. Mu sprague-dawley makoswe, ku Screenafil kuchepetsedwa kwambiri index ya Apoptuctic ndikuwonjezera phosphorylation wa akt ndi enos poyerekeza ndi gulu la owongolera.