RU-58841 Amagwiritsidwa Ntchito Monga Kuteteza Kutaya Tsitsi ndi Kumeta Kwachimuna
Tsatanetsatane wa Zamalonda
| Dzina | RU-58841 |
| Nambala ya CAS | 154992-24-2 |
| Molecular formula | Chithunzi cha C17H18F3N3O3 |
| Kulemera kwa maselo | 369.34 |
| Nambala ya EINECS | 1592732-453-0 |
| Boiling Point | 493.6±55.0 °C(Zonenedweratu) |
| Kuchulukana | 1.39 |
| Mkhalidwe wosungira | Osindikizidwa muumirira, Sungani mufiriji, pansi pa -20°C |
| Fomu | Ufa |
| Mtundu | Choyera |
| Kulongedza | Chikwama cha PE + Chikwama cha Aluminium |
Mawu ofanana ndi mawu
RU58841. onitrile;4--[3-(4-Hydroxybutyl)-4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl]-2-(trifluoroMethyl) ben zonitrile;RU-58841E:candyli(at)speedgainpharma(dot)com;CS-637;RU588841;RU58841;RU58841;RU-58841
Pharmacological Effect
Kufotokozera
RU 58841 (PSK-3841) ndi androgen receptor antagonist yomwe imalimbikitsa kukula kwa tsitsi.RU58841 ndi mankhwala ofufuza omwe amapangidwa kuti azichiza androgenic alopecia, omwe amadziwikanso kuti dazi lachimuna(MPD).
Monga topical anti-androgen, mfundo yake yochitapo si yofanana ndi ya finasteride. Finasteride imagwira ntchito mwachindunji pa 5α reductase, imalepheretsa kutembenuka kwa testosterone kukhala DHT, ndipo imachepetsa zomwe zili mu DHT m'thupi. RU58841 imalepheretsa kuyanjana pakati pa dihydrotestosterone ndi ma follicle atsitsi, sikuchepetsa mwachindunji zomwe zili mu DHT, koma zimachepetsa kumangirira kwa DHT ndi ma follicle receptors a tsitsi, kuti akwaniritse cholinga chochiza androgenetic alopecia.
4--[3- (4-Hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2-(trifluoromethyl) benzonitrile ingagwiritsidwe ntchito ngati mankhwala Chemical synthesis intermediates.Ngati 4--[3- (4-hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2-(trifluoromethyl) benzonitrile ipuma mpweya, Kusuntha wodwalayo ku mpweya wabwino;Mukakhudza khungu, chotsani zovala zowonongeka, tsukani bwino khungu ndi sopo ndi madzi, ndipo funsani kuchipatala ngati kusapeza bwino;
Mbali Zotsatira
RU58841 imagwiritsidwa ntchito pamutu, yotengedwa ndi tsitsi la tsitsi, ndipo mwachidziwitso, imatha kulowa m'magazi ndikukhudza mbali zina za thupi. Koma palibe zokhudza zonse zotsatira zapezeka mu maphunziro apakhungu ntchito anyani. Komabe, anthu ena omwe ayesa RU58841 amanena kuti adakumana ndi zotsatira zina zomwe zingatheke pogwiritsa ntchito RU, kuphatikizapo kuyabwa kwa khungu, kuchepa kwa libido, erectile dysfunction, nseru, maso ofiira, chizungulire, ndi mutu.
