Mecobamanimin ndi yochizira zokhumudwitsa zotumphukira
Tsatanetsatane wazogulitsa
| Dzina | Mecobangemin |
| Nambala ya cas | 13422-555 |
| Mawonekedwe a matope | C63H90C13o14P |
| Kulemera kwa maselo | 1343.4 |
| Malo osungunuka | > 190 ° C (Deco.) |
| Kusalola | DMSO (pang'ono), methanol (pang'ono), madzi (pang'ono) |
| Kukhala Uliwala | 99% |
| Kusunga | Osindikizidwa muuma, sitolo mu freezer, pansi -20 ° C |
| Fumu | Cholimba |
| Mtundu | Ofiira ofiira |
| Kupakila | Pe thumba + aluminium thumba |
Mawuno
Mecobamin; mecobalamine; methylcolambemin; cobalt-methylcolamin;
Pharmacological zotsatira
Ntchito yanyama
MethylcoAmin ndi mankhwala ochizira zotumphukira zamitsempha. Poyerekeza ndi mavitamini B12 Kukonzekera kwa B12, kumabweretsa kubweretsanso kwamphamvu kwa mitsempha. Itha kulimbikitsa ma epulo acid-protein-lipid metabolism kudzera pakusintha kwa methyl ndikukonza minyewa yowonongeka. Imagwira ntchito yopanga ma coenzy Kuphatikiza apo, poyesa kwa maselo ambiri, mankhwalawa amawonjezera ntchito ya methionne kasenza ndipo amalimbikitsa kaphatikizidwe wa myelin lipithin. Kuwongolera kusokonezeka kwa metabolic minofu yamanjenje kumatha kulimbikitsa kaphatikizidwe wa ma axons ndi mapuloteni awo, kupanga kuthamanga kwa mapulani a mafupa pafupi ndi ma axrons. Methylcolanmin imathanso kuletsa kutsitsa kwachilendo kwa minyewa yamitsempha, kumalimbikitsa kusasitsa a erythrobest, ndikuwongolera kuchepa kwa magazi. Methylcoalamin imatha kukonzanso maselo ofiira a magazi, hemoglobin, ndi hematocloct mtengo wa makoswe omwe adachepetsedwa chifukwa cha kuchepa kwa B12. Imagwiritsidwa ntchito ku Megaloblastic Anemia ndi zokhumudwitsa matenda osokoneza chifukwa cha kusowa kwa vitamini B12.
Pharmacological zotsatira
MethylcoAmin ndi yochokera ku Vitamini B12. Amatchedwa mtundu wake. Iyenera kutchedwa "methyl vitamini B12". Itha kulimbikitsa kagayidwe ka mafuta, zimathandizira kaphatikizidwe ka Lecithin mu maselo a Schwann, kukonza gawo lowonongeka meelin, ndikusintha mitsempha yowonjezera; Itha kulowa mwachindunji maselo amitsempha ndikulimbikitsa kusinthika kwa ma axons owonongeka; Yambitsani kapangidwe ka mapuloteni a maselo amitsempha, limbikitsani nkhwangwa ya anabolism, kupewa kuwonongeka kwa axon; Chitani nawo mbali mu kaphatikizidwe wa nucleic acid, kumalimbikitsa ntchito hemotopoietic. Zachipatala, nthawi zambiri zimagwiritsidwa ntchito pochiza matenda ashuga ashuga, ndipo kugwiritsa ntchito nthawi yayitali kumathandizanso pamavuto a mitsempha yayikulu yamagazi. Methylcoban imagwiritsidwa ntchito makamaka pamatenda a mitsempha ya matenda a shuga komanso megaloblac innemia chifukwa chosowa vitamini B12. Amagwiritsidwa ntchito kwambiri ndi zovuta.
Kugwiritsa ntchito
Amagwiritsidwa ntchito pochiritsa matenda amitsempha, sinthani ululu ndi dzanzi, sinthani mofulumira, sinthani ululu woyambitsidwa ndi cervical spondylosis, ndi zina mwadzidzidzi, etc.
