Fmoc-Thr(tBu)-Phe-OH

Fmoc-Thr(tBu)-Phe-OH

Ntchito Yofufuza:
Fmoc-Thr(tBu)-Phe-OH ndi chomangira cha dipeptide chomwe chimagwiritsidwa ntchito kwambiri popanga peptide synthesis (SPPS). Gulu la Fmoc (9-fluorenylmethyloxycarbonyl) limateteza N-terminus, pamene gulu la tBu (tert-butyl) limateteza mbali ya hydroxyl ya threonine. dipeptide yotetezedwayi imaphunziridwa chifukwa cha gawo lake pothandizira kuti peptide italikidwe bwino, kuchepetsa kuthamanga kwamtundu, komanso kutengera mitundu yotsatizana pamapangidwe a mapuloteni ndi maphunziro oyanjana.

Ntchito:
Fmoc-Thr (tBu) -Phe-OH imakhala ngati kalambulabwalo wopangira ma peptide omwe amaphatikizapo zotsalira za threonine ndi phenylalanine, zomwe ndizofunikira kupanga ma hydrogen bond ndi hydrophobic interactions. Unyolo wam'mbali wa threonine umathandizira kuti pakhale polarity ndi malo omwe angakhale a phosphorylation, pomwe phenylalanine imawonjezera mawonekedwe onunkhira komanso kukhazikika kwamapangidwe. Kuphatikiza uku ndikothandiza popanga ma peptides oyesa bioloji, maphunziro omanga ma receptor, komanso kugwiritsa ntchito mankhwala opezeka.