Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH

Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH

Ntchito Yofufuza:
Tetrapeptide yotetezedwayi imagwiritsidwa ntchito mu kaphatikizidwe ka peptide ndi maphunziro ogwirizana. Kuphatikizika kwa Aib (α-aminoisobutyric acid) kumalola ofufuza kuti afufuze mawonekedwe a helical ndi machitidwe opindika mu peptides lalifupi. Magulu ogwira ntchito otetezedwa (Boc, Trt) amawonetsetsa kukhazikika komanso kusankhidwa panthawi yokhazikika ya peptide, ndikupangitsa kuti ikhale chitsanzo chofunikira powerenga mphamvu za msana wa peptide ndi kuyanjana kwa unyolo wam'mbali.

Ntchito:
Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH imagwira ntchito ngati gulu lachitsanzo pofufuza kukhazikika kwa peptide ndi mapangidwe apangidwe. Aib imathandizira kukhazikika kwa helical, pomwe zotsalira za histidine ndi glutamine zimapereka malo omwe angathe kuyanjana nawo, othandiza popanga ma peptides a bioactive kapena kutsanzira zidutswa za mapuloteni. Itha kukhalanso kalambulabwalo wa ma peptides ogwira ntchito pakupanga mankhwala kapena kuyesa kwa biochemical.