Tirzepatide Lyophilized High Purity 99% Peptide Powder 60mg pa vial ya matenda ashuga komanso kuchepa thupi

Tirzepatide Lyophilized Powder (60 mg)

Tirzepatide (LY3298176) ndiye agonist woyamba kuchita pawiri yemwe amalimbana ndi ma GIP (glucose-wodalira insulinotropic polypeptide) ndi GLP-1 (glucagon-like peptide-1) receptors. Adalandira kuvomerezedwa ndi US FDA mu Meyi 2022 kuti azitha kuchiza matenda amtundu wa 2 mellitus (T2DM) monga chothandizira pazakudya komanso masewera olimbitsa thupi.
Mankhwalawa amaperekedwa ngati 60mg lyophilized (wouma-ouma) wosabala ufa mu Mbale, womwe uyenera kubwezeretsedwanso ndi madzi a bacteriostatic isanayambe. Poyerekeza ndi ma GLP-1 receptor agonists amodzi monga semaglutide kapena dulaglutide, tirzepatide imawonetsa kuthandizira kwambiri pakuwongolera kuwongolera shuga m'magazi, kukulitsa chidwi cha insulin, komanso kuthandizira kuchepa thupi kwambiri. Zopindulitsa izi zimatheka chifukwa cha njira yake yolumikizirana ndi ma receptor awiri.

Ubwino waukulu
Glycemic Control

• Imathandizira kutulutsa kwa insulin m'njira yodalira glucose
• Amachepetsa katulutsidwe ka glucagon, amachepetsa shuga wamagazi
• Amatsanzira zotsatira zophatikizana za metabolic za GIP ndi GLP-1

Kuwongolera Kulemera

• Amalimbikitsa kukhuta komanso amachepetsa kudya kwa caloric
• Anawonetsa kuchepa kwakukulu komanso kosalekeza mu maphunziro azachipatala

Moyo wathanzi

• Zambiri zoyambira zikuwonetsa kuchepa kwachiwopsezo chamtima kwa odwala omwe ali ndi T2DM

Kagwiritsidwe ndi Mlingo

• Tirzepatide lyophilized ufa (60 mg) ayenera reconstituted ndi bacteriostatic madzi pamaso ntchito. Kuwongolera kumachitika pogwiritsa ntchito jakisoni wa subcutaneous, nthawi zambiri kamodzi pamlungu tsiku lomwelo sabata iliyonse.

Type 2 shuga mellitus

• Mlingo woyambira: 2.5 mg kamodzi pa sabata
• Titration: Wonjezerani milungu inayi iliyonse monga momwe mwalekerera
• (→ 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg → 20 mg → 30 mg → 45 mg → mpaka 60 mg)
• Mlingo wamba: 10-30 mg mlungu uliwonse
• Pazipita Mlingo: 60 mg mlungu uliwonse

Kunenepa Kwambiri / Kulemera Kwambiri

• Mlingo woyambira: 2.5 mg kamodzi pa sabata
• Titration: Kuwonjezeka kwapang'onopang'ono kwa mlingo monga momwe kulekerera
• (2.5 → 5 → 7.5 → 10 → 12.5 → 15 → 20 → 30 → 45 → 60 mg)
• Mlingo wamba: 30-60 mg mlungu uliwonse
• Pazipita Mlingo: 60 mg mlungu uliwonse

Analimbikitsa Mlingo Kuyerekeza

Zindikirani:Onetsetsani kuti mlingo uliwonse wam'mbuyo umalekerera bwino musanakwere.

Zomwe Zingachitike

• M'mimba: Mseru, kusanza, kutsekula m'mimba, komanso kusapeza bwino m'mimba (nthawi zambiri panthawi yoyambira).
• Hypoglycemia: Chiwopsezo chochepa kwambiri, koma chimachulukira tikaphatikizidwa ndi mankhwala ena ochepetsa shuga
• Jekeseni Site Zochita: Kufiira, kuyabwa, kutupa, kapena kupweteka pang'ono pamalowo
• Pancreatitis: Zosowa koma zotheka; kuyang'anira kupweteka kwa m'mimba kosalekeza
• Zotsatira za aimpso: Kuyang'anira ntchito ya impso kungafunike mwa anthu ena

Pharmacokinetics

• Hafu ya Moyo: Pafupifupi sabata imodzi
• Mlingo pafupipafupi: Imathandiza yabwino kamodzi pamlungu makonzedwe

Chidule
Tirzepatide 60 mg lyophilized ufa imayimira chithandizo cham'badwo wotsatira, kuphatikiza kuwongolera kwamphamvu kwa glycemic ndikuchepetsa kwambiri kuwonda komanso chitetezo chamtima.
Ndi ndandanda yapang'onopang'ono ya titration (2.5 mg → mpaka 60 mg), imalola kulolera kowonjezereka komanso kusinthasintha kwa chithandizo chamunthu payekha. Kayendetsedwe kake kamodzi pa sabata kumapangitsa kuti anthu azitsatira bwino, ndikupangitsa kukhala njira yabwino komanso yothandiza pakuwongolera matenda a shuga amtundu wa 2 komanso kunenepa kwambiri pazachipatala komanso kafukufuku wapamwamba.