Tirzepatide ndi mankhwala atsopano omwe akuyimira kupambana kwakukulu kwa matenda a shuga a 2 komanso kunenepa kwambiri. Ndiye agonist woyamba wapawiri wa insulinotropic polypeptide (GIP) yodalira glucose ndi glucagon-like peptide-1 (GLP-1) receptors. Kachitidwe kapadera kameneka kamasiyanitsa ndi machiritso omwe alipo kale ndipo amathandizira kwambiri pakuwongolera shuga wamagazi komanso kuchepetsa thupi.
Poyambitsa GIP ndi GLP-1 zolandilira, Tirzepatide imathandizira katulutsidwe ka insulini komanso kumva, imachepetsa katulutsidwe ka glucagon, imachepetsa kutulutsa m'mimba, komanso imachepetsa chilakolako.
Imayendetsedwa ngati jekeseni kamodzi pamlungu, Tirzepatide yawonetsa mphamvu yodabwitsa m'mayesero azachipatala. Imawongolera kwambiri kuwongolera kwa glycemic ndikuchepetsa kulemera kwa thupi, nthawi zambiri kuposa momwe mankhwala omwe alipo panopa. Kuonjezera apo, ubwino wa mtima wamtima wawonedwa.
Zotsatira zofala kwambiri ndi m'mimba, kuphatikizapo nseru, kutsekula m'mimba, ndi kusanza, zomwe nthawi zambiri zimakhala zochepa kwambiri ndipo zimachepa pakapita nthawi.
Ponseponse, chitukuko cha Tirzepatide chikuwonetsa malire atsopano pochiza matenda a metabolic, kupereka chida champhamvu chowongolera matenda a shuga komanso kunenepa kwambiri.
Nthawi yotumiza: Sep-01-2025