Rhovac Khansa Puptide Katemera RV001 kuti apatsidwa ndi ofesi yanzeru yaku Canada

Canada nthawi 2022-50, Kampani yopanga mankhwala yofananira ndi imfoology, adalengeza kuti ntchito yake ya patent (No. 2710061) Chifukwa cha ntchito yake ya khansa ya patenti ya RV001 idzavomerezedwa ndi ofesi yaluntha ya Canada (CIPO). M'mbuyomu, kampaniyo yapeza ma Patent okhudzana ndi RV001 ku United States, Europe ndi Japan. Kugonjera kwapate kudzapereka chitetezo chokwanira kwa RV001 m'misika yayikulu ndikukweza zotchinga za kampani.

Monga momwe anaperekera kale, patent iyi imafotokoza katemera wa rv001 ndi mitundu yake, komanso kugwiritsidwa ntchito kwake pochiza / kupewa khansa ya phocc. Pakati pawo, a Rhoc ndi chotupa - chogwirizanitsa (taa) chomwe chimapitilira mumitundu yosiyanasiyana. Zowona nthawi yomweyo, patent idzatha mu 2028-12 ndipo ikuyembekezeka kukulungidwa mukapeza satifiketi yothandizira (CSP).

01 Indilcamothide

Onilcamotide ndi katemera wa khansa yopangidwa ndi immunogenic mapepu omwe amachokera ku chiwalo cha amayi am'banja C (RHOC), omwe amatha kusinthidwa mu batire ya mthupi C). Subcutaneous makonzedwe a Onilcamotide imathandizira chitetezo cha mthupi lotsogola ndi cytotoxic tlytete (CTL) Kuyankha kotupa, motero kunadzutsa maselo otupa.

2020-11, RV001 idapatsidwa njira yofulumira ya FDA.

Mayesero azachipatala

Mu 2018, gawo lomwe ine / IIA Chachipatala cha Onilcamotide zochizira khansa ya prostate idavomerezedwa, ndipo odwala 21 adalembetsa. Zotsatira zake zinawonetsa kuti Olilcamotide anali otetezeka komanso olekeredwa bwino. Kuphatikiza apo, odwala amakhala ndi mayankho ogwira mtima komanso okhazikika potsatira chithandizo. Mu 2021, kutsatira kwa masiku 19 mwa maphunzirowa, patatha zaka zitatu atamaliza kulandira chithandizo ndi mbuye wa phope, adawonetsa kuti maphunzirowa sanakonzenso za metastase iliyonse kapena kunalandira chithandizo chothandiza kwambiri (chasa). . Mwa awa, maphunziro 16 analibe sasita odziwika, ndipo maphunziro atatu anali atachedwetsa za PSA za PSASA. Psa ndi mapuloteni opangidwa ndi prostate gland ndipo imagwiritsidwa ntchito potsatira zomwe zakhala khansa ya prostate yodziwika bwino.

Mu 2019, a RV001 Gawo la Cushilling Bravac (wachilendo, wakhungu, placebo-olamulidwa kuti azitha kupanga khansa yamphamvu popewa opaleshoni / radiation. Kuyeserera kumeneku ndi kokhudza nkhani zamayiko ena, ku Denmark, Finland, Sweden, Sweden, Belgium, ndi United States. Mlanduwo unamaliza kusonkhana wodwala mu 2021-09, omwe ali ndi maphunziro pafupifupi 175 omwe adalembetsa, ndipo adzatha mu 2022h1. Kuphatikiza apo, mapulani a rovac kuchititsa maphunziro azomwe amayesa maphunziro omwe akufuna kupereka umboni wowonjezera pakukula kwa RV001 mu zisonyezo.

Kuphatikiza apo, Komiti Yoyang'anira Chitetezo inkapangitsanso chidwi cha RV001 mu 2021-07, ndipo palibe zochitika zovuta zosayembekezereka zomwe zidapezeka, zomwe zinali zachipatala zapita.