Motixafortide

Motixafortide API

Motixafortide ndi peptide yotsutsana ndi CXCR4 yopangidwa kuti ilimbikitse maselo amtundu wa hematopoietic (HSCs) kuti alowetsedwe ndi autologous ndipo akuphunziridwanso mu oncology ndi immunotherapy.

Njira & Kafukufuku:

Motixafortide imatchinga axis ya CXCR4-SDF-1, zomwe zimatsogolera ku:
Kuthamangitsidwa kwa stem cell kulowa m'magazi ozungulira
Kupititsa patsogolo kugulitsa kwa chitetezo chamthupi komanso kulowa kwa chotupa
Kuthekera kolumikizana ndi ma checkpoint inhibitors ndi chemotherapy

Zawonetsa zokolola zapamwamba za stem cell poyerekeza ndi olimbikitsa omwe alipo m'mayesero azachipatala.
Mawonekedwe a API (Gentolex Gulu):

Peptide yapamwamba kwambiri yopangidwa
Miyezo yopanga ngati GMP
Oyenera jekeseni formulations

Motixafortide API imathandizira kafukufuku wapamwamba mu stem cell therapy ndi khansa immunotherapy.