Glepaglutide

Glepaglutide API

Glepaglutide ndi analogue ya GLP-2 yanthawi yayitali yopangidwira kuchiza matenda am'mimba (SBS). Imawonjezera kuyamwa kwamatumbo ndi kukula, kuthandiza odwala kuchepetsa kudalira zakudya za makolo.

Njira & Kafukufuku:

Glepaglutide imamangiriza ku glucagon-ngati peptide-2 receptor (GLP-2R) m'matumbo, ndikulimbikitsa:
Kukula kwa mucous nembanemba
Kupititsa patsogolo kuyamwa kwa michere ndi madzimadzi
Kuchepetsa kutupa kwamatumbo

Kafukufuku wazachipatala awonetsa kuti Glepaglutide imatha kukulitsa ntchito yamatumbo ndikuwongolera moyo wa odwala a SBS.

Mawonekedwe a API (Gentolex Gulu):

Analogue ya peptide yayitali
Opangidwa kudzera pa solid-phase peptide synthesis (SPPS)
Kuyera kwakukulu (≥99%), mtundu wa GMP

Glepaglutide API ndi chithandizo chodalirika cha kulephera kwa matumbo komanso kukonzanso matumbo.