Fmoc-L-Ls[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Ls[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH ndi chipika chomangira cha amino acid chomwe chimapangidwa kuti chizigwiritsidwa ntchito popereka mankhwala ndi bioconjugation. Imakhala ndi gawo la Eic (eicosanoid) lolumikizana ndi lipid, γ-Glu polunjika, ndi ma spacers a AEEA kuti athe kusinthasintha.

 
Kafukufuku & Ntchito:

Amagwiritsidwa ntchito popanga ma prodrug synthesis, chitukuko cha ADC, ndi kapangidwe ka nanocarrier

Imakulitsa kulunjika kwa membrane, kusungunuka, ndi kugwirizanitsa bwino

Oyenera SPPS mu kafukufuku wapamwamba wa peptide-drug conjugate

Zogulitsa (Gentolex Gulu):

Fmoc-otetezedwa, kuyera kwakukulu (≥99%)

Lili ndi magulu a OtBu omwe amatha kuthyoledwa kuti azitha kuwongolera

Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH ndi yabwino kwa machitidwe operekera olondola komanso kapangidwe kake ka peptide.