Fitusiran

Fitusiran (API)

Ntchito Yofufuza:
Fitusiran API ndi kaphatikizidwe kakang'ono kosokoneza RNA (siRNA) komwe kumafufuzidwa makamaka pankhani ya hemophilia ndi matenda a coagulation. Imalimbana ndiantithrombin (AT kapena SEPINC1)jini m'chiwindi kuti achepetse kupanga kwa antithrombin. Ofufuza amagwiritsa ntchito Fitusiran kuti afufuze njira za RNA interference (RNAi), kuletsa jini yeniyeni ya chiwindi, ndi njira zatsopano zochiritsira zochepetsera coagulation mu hemophilia A ndi B odwala, kapena opanda zoletsa.

Ntchito:
Fitusiran imagwira ntchito poletsa mawu a antithrombin, anticoagulant yachilengedwe, potero imakulitsa kupanga kwa ma thrombin ndikulimbikitsa mapangidwe a magazi. Makinawa amapereka njira yochepetsera magazi mwa odwala omwe ali ndi hemophilia. Monga API, Fitusiran imagwira ntchito ngati gawo lothandizira pazamankhwala omwe amatenga nthawi yayitali kuti apititse patsogolo moyo wabwino komanso kuchepetsa kulemedwa kwamankhwala pazovuta zamagazi.