BPC-157

BPC-157 API

BPC-157 (dzina lonse: Body Protection Compound 157) ndi peptide yochepa yopangidwa ndi 15 amino acid, yochokera ku mndandanda wa mapuloteni oteteza zachilengedwe mu madzi a m'mimba mwa munthu. Zawonetsa mphamvu zambiri zokonzanso minofu ndi zotsutsana ndi zotupa m'maphunziro oyesera ndipo zimawonedwa kuti ndi munthu wodalirika kwambiri wogwiritsa ntchito mankhwala a peptide.

Monga mankhwala opangira mankhwala (API), BPC-157 yakhala ikugwiritsidwa ntchito m'madera ambiri a kafukufuku wa sayansi padziko lonse lapansi kuti afufuze zochitika zake zamoyo m'matumbo a m'mimba, musculoskeletal system, dongosolo lamanjenje, dongosolo la mtima ndi kukonzanso minofu yofewa, makamaka pakukonza zowawa komanso kafukufuku wotsutsa-kutupa.

Research ndi pharmacological limagwirira ntchito

BPC-157 yaphunziridwa kwambiri, makamaka mu kuyesa kwa nyama mu vivo ndi ma cell a vitro cell, ndipo yapezeka kuti ili ndi zotsatirazi zazikulu zachipatala:

1. Kusinthika kwa minofu ndi kukonza zoopsa

Imalimbikitsa kusinthika kwa tendon, ligament, mafupa ndi minofu yofewa, ndipo imatha kupititsa patsogolo angiogenesis (angiogenesis).

Kufulumizitsa machiritso a bala, kukonzanso pambuyo pa opaleshoni ndi kubwezeretsanso kuvulala kwa minofu yofewa, yomwe yatsimikiziridwa mu zitsanzo za nyama monga kupasuka kwa tendon, kupsinjika kwa minofu, ndi fracture.

2. Kuteteza ndi kukonza m'mimba

Mu zitsanzo monga chapamimba chilonda, enteritis, ndi colitis, BPC-157 ali kwambiri mucosal zoteteza kwenikweni.

Ikhoza kukana kuwonongeka kwa m'mimba chifukwa cha mankhwala osagwiritsidwa ntchito ndi anti-inflammatory (NSAIDs) ndikulimbikitsa machiritso a m'mimba.

3. Anti-yotupa ndi immunomodulatory

Imayang'anira chitetezo chamthupi mwa kuletsa zinthu zoyambitsa kutupa (monga TNF-α, IL-6) ndikuwongolera zinthu zotsutsana ndi zotupa.

Ili ndi phindu lomwe lingakhalepo ngati chithandizo chothandizira matenda otupa osatha monga ** nyamakazi ya nyamakazi ndi matenda otupa a m'matumbo (IBD) **.

4. Neuroprotection ndi neurogeneration

Mu zitsanzo pambuyo pa kuvulala kwa msana, kusokonezeka kwa mitsempha, ndi zochitika za cerebrovascular, BPC-157 ikhoza kulimbikitsa kusinthika kwa mitsempha ndi kuchepetsa kuwonongeka kwa mitsempha.

Itha kulimbana ndi zovuta zama neuropsychiatric monga nkhawa, kukhumudwa, komanso kudalira mowa (gawo loyesera).

5. Chitetezo cha mtima ndi mitsempha

BPC-157 ikhoza kupititsa patsogolo kufalikira kwa mitsempha ndikulimbikitsa kukonza kwa microvascular, ndipo imakhulupirira kuti imakhala ndi zotsatira zabwino pa matenda monga myocardial ischemia, venous thrombosis, ndi kuvulala kwa mitsempha.

Zotsatira za kafukufuku woyeserera komanso wotsimikizira

Ngakhale kuti BPC-157 sinavomerezedwe mofala kuti ikhale ndi mankhwala olembedwa ndi anthu, yasonyezedwa poyesera nyama:

Kuthamanga kwakukulu kwa nthawi yokonza minofu (monga 50% kuthamangitsa machiritso a tendon)

Kuchepetsa kwambiri kuchuluka kwa magazi m'mimba, kuvulala kwamatumbo, ndi zilonda zam'mimba

Kupititsa patsogolo kayendedwe ka mitsempha ya mitsempha ndikuwonjezera ntchito ya malo osadziwika

Kuchulukitsa angiogenesis ndi kuchuluka kwa mapangidwe a minofu ya granulation

Chifukwa cha zotsatirazi, BPC-157 ikukhala molekyulu yofunikira pakufufuza pambuyo pa zoopsa, kuvulala pamasewera, matenda am'mimba, komanso matenda a neurodegenerative.
Kupanga kwa API ndi kuwongolera khalidwe

BPC-157 API yoperekedwa ndi Gulu lathu la Gentolex imatengera njira yolimba ya gawo (SPPS) ndipo imapangidwa pansi pamikhalidwe ya GMP. Lili ndi izi:

Kuyera kwakukulu: ≥99% (kuzindikira kwa HPLC)

Zotsalira zazing'ono zonyansa, palibe endotoxin, palibe kuipitsidwa kwachitsulo cholemera

Kukhazikika kwa batch, kubwereza mwamphamvu, kugwiritsa ntchito mlingo wa jakisoni

Thandizani magalamu ndi ma kilogalamu kuti mukwaniritse zosowa zamagawo osiyanasiyana kuchokera ku R&D kupita kumakampani.